Case Files: Microbiology, 2nd Edition
Format: PDF / Kindle (mobi) / ePub
More than 50 clinical cases help you excel in your microbiology coursework and on the USMLE Step 1
The Case Files series is an award-winning learning system proven to improve exam scores. This series helps you to learn in the context of real patients instead of simply memorizing. Case Files: Microbiology: Second Edition presents 50+ clinical cases with open-ended questions which weave basic science concepts into the clinical scenario. Each case includes an extended discussion (including definitions and a pathophysiology discussion), key points, and 3-5 USMLE-style comprehension questions. The authors are experienced teachers from the University of Texas-Houston Medical School in Houston, Texas and Loma Linda University School of Medicine in Loma Linda, California.
for the patient’s illness: The nematode, Ascaris lumbricoides. • How did the patient become infected: By ingesting eggs of the parasite that have matured in an external environment to contain a larval form. CLINICAL CORRELATION Infections with Ascaris are frequently asymptomatic or may be accompanied by numerous symptoms. The pathology that underlies symptoms is conditioned by the number of worms harbored and the sequential location of larvae in the lungs and adult worms in the intestine.
enter the circulation and migrate to the liver, where they mature into adult male and female worms. The adult worms migrate via the bloodstream to their final locations. S. mansoni and S. japonicum descend to the mesenteric veins and S. haematobium to the vesical plexus. Gravid female worms may release 300 to 3000 eggs per day during a 5- to 10-year life span. Eggs of S. haematobium can work their way through the wall of the urinary bladder into the lumen and are eliminated in urine, while eggs
distribution, while infections with other vectors, such as lice, fleas, and mites, have worldwide distribution. Disease caused by R. rickettsii are most commonly associated with the dog tick in the southeastern states and the West Coast and the wood tick in the Rocky Mountain states and southwestern Canada, while other tick vectors have been identified in South and Central America. Hard ticks are the primary reservoirs and vectors, with the most frequent disease presented from April to September.
detection assay 6.3 A hospitalized patient developed severe diarrhea and pseudomembranous colitis within 5 days after antibiotic therapy was initiated. The severe diarrhea and pseudomembranous colitis occurred as a result of which of the following? A. Collagenase B. Fibrinolysin C. Hyaluronidase D. Lecithinase E. Mucinase F. Toxins A and B ANSWERS 6.1 D. The use of broad-spectrum antibiotics such as ampicillin and clindamycin has been associated with pseudomembranous colitis. Antibiotic
bladder during instrumentation or sexual intercourse. Those serotypes that produce adhesions that mediate adherence of the organisms to epithelial cells in the urinary tract, are more likely to cause infections. The majority of cases of uncomplicated and complicated pyelonephritis are caused by E. coli, a complication of UTI in which the organisms continue to ascend from the bladder to the kidney. APPROACH TO: Suspected Escherichia Coli UTI OBJECTIVES 1. Know the structure, characteristics,