Dermatopathology Primer of Cutaneous Tumors
Format: PDF / Kindle (mobi) / ePub
Dermatopathology Primer of Cutaneous Tumors presents a detailed overview of the most common skin neoplasms. For each neoplasm, the epidemiology, pathophysiology, clinical features, clinical variants, and special studies are presented in a succinct, bulleted form. Extensive illustrations demonstrate each neoplasm’s characteristic features, as well as those of other tumors in the histological differential.
The book covers both benign and malignant cysts, epidermal, melanocytic, lymphoid, and soft tissue neoplasms. It complements the Dermatopathology Primer of Inflammatory Diseases, written by authors of the same team.
These books introduce the basic concepts of dermatopathology to medical students and residents training in pathology and dermatology as well as to other health care professionals seeking a resource for a basic understanding of dermatopathology.
Offered in an easy-to-read format, the book provides a basic understanding of dermatopathology on which further, deeper learning can be added, as well as a quick visual reference to refresh the learner on the important points of each diagnosis. A reference section and glossary are included for the benefit of non-dermatology specialists.
congenital examples have been documented • Familial cases may be seen and usually present with multiple lesions 1. Pigmented spindle-shaped melanocytes 2. Thickened collagen bundles in mid and upper dermis Epithelioid blue nevus: • Dermal aggregates of round to oval melanocytes • Centrally placed nuclei (fried egg appearance) • Coarse granules of melanin in their cytoplasm Pathophysiology Deep penetrating nevus: • Vertically oriented neoplasm • Epithelioid and spindle melanocytes in
choice 55 K24690.indd 55 Clinical Variants • None 15/06/2015 16:06 Porocarcinoma Introduction Porocarcinoma is a rare aggressive malignant adnexal neoplasm of sweat gland duct. Epidemiology • Porocarcinomas represent 0.005–0.01% of all malignant cutaneous tumors • It is primarily a tumor of elderly adults, 1 50–80 years of age, although it has been reported in young adults • There is no predilection for either gender Pathophysiology • The etiology of theses tumors remains unknown,
and recently it has been demonstrated the presence of papillomavirus DNA in these lesions. Histological features 1. Small circumscribed and lobular or multilobular proliferation of pale keratinocytes 2. Peripheral palisading of the nuclei 3. Outlined by a thick densely eosinophilic basement membrane 4. Numerous squamous eddies Epidemiology • The majority of trichilemmoma occur between the age of 20 and 80 years, with a mean age of 30 years • Male-to-female ratio is approximately 1:1 •
Dermatopathology. New York: McGraw-Hill; 2010: 697–8. Mehregan AH, Brownstein MH. Pilar sheath acanthoma. Arch Dermatol 1978:114:1495–97. Tumor of the follicular infundibulum Malignant melanomas and variants Barnhill, R, Crowson AN, Magro CM, Piepkorn MW. Tumor of the follicular infundibulum. In Dermatopathology. New York: McGraw-Hill; 2010: 697,700. McCalmont T. Adnexal neoplasms. In Bolognia J, Jorizzo J, Schaffer J (eds) Dermatology 3e. Philadelphia: Elsevier/ Saunders; 2012: 1837–8. Elder
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